Challenge of quality evaluation of traditional Chinese medicinal materials and application progress on metabolomic approach in its quality valuation

LI Zhen-yu1 CUI Yi-fan1 QIN Xue-mei1

(1.Modern Research Center for Traditional Chinese Medicine, Shanxi University, Taiyuan, China 030006)

【Abstract】Traditional Chinese medicinal materials (TCMM) are the material basis for traditional Chinese medicine (TCM), and the quality of the herbals was closely related with the efficacy and safety of TCM in clinic. Aiming at the difficulty in the quality evaluation of TCMM, some genuine herbals in Shanxi province, such as Astragali Radix, Farfarae Flos, and Buplerui Radix, were used as example, to investigate the application potential of the metabolomic approach. In order to lay the foundation for the accurate quality evaluation and further improvement of quality standard of TCMM, the studies in the recent ten years were summarized, and the prospect as well as the future research focus was also discussed.

【Keywords】 metabolomics; traditional Chinese medicinal materials; quality evaluation; traditional Chinese medicine; quality standard;

【DOI】

【Funds】 National Natural Science Foundation of China (31770362, 31570346, 31270008, 30900118, 31100244) Key Team of Shanxi Provincial Science and Technology Innovation (201705D131028-17)

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This Article

ISSN:0253-2670

CN:12-1108/R

Vol 49, No. 10, Pages 2221-2229

May 2018

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Article Outline

Abstract

  • 1 Chemical analysis of metabolomes
  • 2 Integration analysis of metabolomics and other technologies
  • 3 Conclusions and prospect
  • References