Efficacy analysis on type 2 diabetes mellitus treated with acupuncture in females

WANG Yuan1 LIU Zhi-cheng1 XU Bin1

(1.Provincial Co-Construction Education Administration Key Laboratory Room of Integrated Acupuncture and Medicine, Nanjing University of CM, Nanjing Jiangsu Province, China 210029)
【Novelty】This study evaluated the efficacy and the relevant effect factors of acupuncture for type 2 diabetes mellitus (T2DM) in females. The changes in fasting plasma glucose (PFG), fasting insulin (FINS), insulin sensitivity index (ISI), insulin resistace index (Homa-IR), index of islet β-cell function (Homa-β), total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C) and high density lipoprotein cholesterol (HDL-C) were compared before and after three courses of treatment between two groups, one with deficiency of kidney yin syndrome and the other with yin and yang deficiency syndrome. The relationship of the efficacy was analyzed in terms of the syndrome differentiation, age, duration of sickness, obesity and hereditary factors. Results showed that acupuncture could positively regulate the glucose and lipid metabolism in the patients of T2DM. This therapy improved insulin resistance, enhanced the body sensitivity to insulin and improved insulin β-cell function. The younger the patient was, the better the efficacy was.

【Abstract】 Objective To evaluate the efficacy and the relevant effect factors of acupuncture for type 2 diabetes mellitus (T2DM) in females. Methods Of 83 female patients of T2 DM, 49cases were deficiency of kidney yin syndrome and 34 cases were yinand yangdeficiency syndrome. Acupuncture was adopted and the acupoints were selected according to the syndrome differentiation. In kidney yin deficiency syndrome, Taixi (KI 3), Shenmen (HT 7), Taichong (LR 3) and Sanyinjiao (SP 6), etc. were selected. In yin and yang deficiency syndrome, Shenshu (BL 23), Pishu (BL 20), Yishu (Extra) and Jingmen (GB 25), etc. were selected. In 3 courses of treatment, the changes in fasting plasma glucose (FPG), fasting insulin (FINS), insulin sensitivity index (ISI), insulin resistace index (Homa-IR), index of islet β-cell function (Homa-β), total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C) and high density lipoprotein cholesterol (HDL-C) were compared before and after treatment between the two groups. The relationship of the efficacy was analyzed in terms of the syndrome differentiation, age, duration of sickness, obesity and hereditary factors. Results After the treatment,the levels of FPG, FINS, Homa-IR, TC, TG and LDL-C were reduced obviously (all P<0.01) and the levels of ISI, Homa-β and HDL-C were increased apparently (all P < 0.01). The total clinical effective rate was 80.7% (67/83), in which, that of kidney yin deficiency syndrome was 83.7% (41/49) and that of yin and yang deficiency syndrome was 76.5% (26/34). The efficacy was not different significantly between the two syndromes. But, the younger the age was, the better the efficacy was. Conclusion Acupuncture positively regulates the glucose and lipid metabolism in the patients of T2 DM. This therapy improves insulin resistance, enhances the body sensitivity to insulin and improves insulin β-cell function. The efficacy is related to the patient’s age.

【Keywords】 type 2 diabetes mellitus; lower xiao; acupuncture therapy; pattern/syndrome differentiation;

【DOI】

【Funds】 National Natural Science Foundation of China (30873307, 39770929) Specialized Research Fund Project for Doctoral Programs in Colleges and Universities (20040315008)

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This Article

ISSN:0255-2930

CN:11-2024/R

Vol 34, No. 01, Pages 21-24

January 2014

Downloads:43

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Abstract

  • 1 Clinic data
  • 2 Treatment methods
  • 3 Efficacy observation
  • 4 Results
  • 5 Discussion
  • References