Effect of acupoint catgut embedding, fire needle, and auricular acupuncture on female post-adolescent acne and serum sexual hormone

LU Wen1 ZHU Ligang2 TIAN Qianmo3 BAI Xinyu1 KUANG Weiwei4 FANG Zhongnv5 REN Hong4 CHEN Renqiong4 XIE Chuntao4

(1.Department of Acupuncture-Moxibustion and Tuina, the First People’s Hospital of Lianyungang, Lianyungang, Jiangsu Province, China 222002)
(2.Department of Clinical Laboratory, the First People’s Hospital of Lianyungang, Lianyungang, Jiangsu Province, China 222002)
(3.Affiliated Hospital of Nanjing University of Chinese Medicine)
(4.Department of Dermatology, the First People’s Hospital of Lianyungang, Lianyungang, Jiangsu Province, China 222002)
(5.Medical Examination Center, the First People’s Hospital of Lianyungang, Lianyungang, Jiangsu Province, China 222002)

【Abstract】Objective To compare the difference in serum sexual hormone between female patients with post-adolescent acne and healthy women, and to explore the efficacy and action mechanism of acupoint catgut embedding, fire needle, and auricular acupuncture on skin lesion in female patients of post-adolescent acne. Methods A total of 107 female patients with post-adolescent acne were divided into an integrated acupuncture group (54 cases, four cases were excluded) and a medication group (53 cases, five cases were excluded). The patients in the integrated acupuncture group were treated with comprehensive treatment of acupoint catgut embedding, fire needle, and auricular acupuncture. The acupoint catgut embedding was applied at Dazhui (GV 14), Yintang (GV 29), Yangbai (GB 14) through Yuyao (EX-HN 4) and other acupoints based on syndrome differentiation; The fire needling was applied at skin lesion. The auricular acupuncture was applied at Erjian (EX-HN 6), e (AT1), kou (CO1), etc. The patients in the medication group were treated with oral administration of tanshinone capsules (four capsules each time, three times a day) and external use of adapalene gel (one treatment per day at night). Patients in the two groups were treated for eight weeks. The skin lesion of acne was evaluated before treatment as well as four weeks and eight weeks after treatment in the two groups. The serum levels of testosterone (T) and estradiol (E2) were tested 24 hours before menstruation in the integrated acupuncture group (50 cases) and healthy control group (46 cases), and the change of serum sexual hormone after treatment was observed in 21 patients with sexual hormone disorder in the integrated acupuncture group. Results Before treatment, the level of E2 in the integrated acupuncture group was significantly lower than that in the healthy control group (P < 0.01), but T/E2 in the integrated acupuncture group was significantly higher than that in the healthy control group (P < 0.01). After treatment, the level of E2 was significantly increased (P < 0.01) and T/E2 was reduced (P < 0.01) in the 21 patients with sexual hormone disorder in the integrated acupuncture group. The skin lesion scale of acne was significantly reduced in the two groups after four-week and eight-week treatment (all P < 0.01). The difference between the two groups was not significant after four-week treatment (P > 0.05). The skin lesion scale of acne in the integrated acupuncture group was significantly lower than that in the medication group after eight-week treatment (P < 0.01). The efficacy between the two groups was not significant after four-week the treatment (P > 0.05). After eight-week treatment, the cured and effective rate was 66.0% (33/50) in the integrated acupuncture group, which was superior to 45.8% (22/48) in the medication group (P < 0.05). Conclusion Compared with healthy women, the level of serum sexual hormone of E2 is reduced in the female patients of post-adolescent acne, resulting in relative increased level of T. The acupoint catgut embedding, fire needle, and auricular acupuncture have better efficacy than medication for post-adolescent acne, which have regulation effects on sexual hormone disorder.

【Keywords】 acne, female adolescence; acupoint catgut embedding; fire needle; auricular acupuncture; testosterone (T) ; estradiol (E2) ;

【DOI】

【Funds】 Science and Technology Project of Jiangsu Provincial Bureau of Traditional Chinese Medicine (PY 201510) Research Fund for Doctoral Program of the First People’s Hospital of Lianyungang

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(Translated by LU R)

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This Article

ISSN:0255-2930

CN:11-2024/R

Vol 38, No. 08, Pages 833-838

August 2018

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Article Outline

Abstract

  • 1 Clinical data
  • 2 Treatment methods
  • 3 Observation of therapeutic effects
  • 4 Discussion
  • References