This method makes the research on the prevention and treatment of cerebral small vessel diseases with TCM fairly self-explanatory

Sep. 2,2022
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The incidence of cerebral small vessel diseases (CSVDs), the common neurological diseases, has been increasing year by year around the world. Since CSVDs may lead to many sequelae, such as hemorrhagic stroke, vascular cognitive impairment, and epilepsy, they cause a huge economic burden to society. However, one of the biggest challenges is that there are limited methods of evaluation of CSVDs before the development of clinical sequelae. In recent years, TCM has provided new entry points for the intervention and treatment of CSVDs during the early and whole pathological process, and obtained satisfactory results. Then, what are the current situation of the research and the future trend in the field of TCM against CSVDs?

Two useful tools, CiteSpace and Gephi, are recommended here. CiteSpace can visualize new trends and fundamental changes in a discipline over time, which can be used to explore the dynamics of a discipline and the time variation map from the knowledge base to the research frontier. Therefore, it is a type of analysis software presenting the innovative combination of computing technology and visualization technology. Gephi is a type of free and open-source visualization software based on Java for complex network analysis, which can be used for network and exploratory analysis of data.

LI Ting-ting and GAO Ying et al. from Beijing University of Chinese Medicine published the research “Analysis of Citespace knowledge map for traditional Chinese medicine prevention and treatment of cerebral small vessel diseases” in China Journal of Chinese Materia Medica, in which they analyzed the research on the prevention and treatment of CSVDs with TCM based on knowledge map, and preliminarily explored the research hotspots and trends. To be specific, articles on the treatment of CSVDs with TCM in China National Knowledge Infrastructure (CNKI), Wanfang, and VIP Chinese Journal Service Platform (VIP) (from the establishment of the databases to November 2021) were retrieved by CiteSpace 5.7 R4 and Gephi, followed by bibliometric analysis. The generation of maps on the annual number of articles, author cooperation network, institution cooperation network, keyword co-occurrence, keyword clustering, and keyword emergence were drawn and analyzed. A total of 277 authors were included in the author cooperation network, represented by CHEN Zhi-gang, and 87 institutions were included in the institution cooperation network, represented by Dongfang Hospital of Beijing University of Chinese Medicine. Keyword clustering showed that research on the treatment of CSVDs with TCM mainly focused on five aspects, including the related disease research, neurological function deficits, disease nature and location in TCM, TCM treatment methods, and formulas. The prevention and treatment of CSVDs with TCM have been developing steadily in the past decades, and TCM has unique advantages in the prevention and treatment of this disease. The knowledge map vividly demonstrates the development, research hotspots, and trends in this field, providing references for further research.

This research was supported by the National Key Research and Development Program. The research results were published in China Journal of Chinese Materia Medica, Vol. 47, No. 6, 2022. The original research paper is available in dbcode=CJFD&dbname=CJFDLAST2022&filename=ZGZY202208027&uniplatform=NZKPT&v=zoPwKB8LthAwsbVy_HhiKyKM_fl4eWHEVeBG7RLjNzeFFr6GjcCazIf8hd_VeXtf

Corresponding Author: LI Ting-ting
CNKI Press Officer: LI Jingjing YANG Na

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